
It doesn’t have to be fish:
Plant-based Omega-3 with DHA & EPA continues to trend!

The polyunsaturated omega-3 fatty acids (PUFAs) include α-linolenic acid, stearidonic acid, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA). They are associated with many positive health properties, with a wide range of effects on cardiovascular diseases, diabetes, containercer, Alzheimer's, dementia and depression. [1] The two omega-3 fatty acids (EPA) and (DHA), which are contained in almost every omega-3 food supplement, play an outstanding role here. They container be obtained from fish or from algae oil (vegan variant).
It is important when taking Omega-3 supplements that they are taken with the main meal that is rich in fat, as this allows the body to absorb up to 13 times more of them [2] A high-fat meal stimulates the liver's production of bile acid, which emulsifies the fatty acids and makes them easier to digest and absorb [3] .
Algae oil – vegan Omega-3 alternative
A good source of plant-based omega-3 with DHA and EPA is the microalgae Schizochytrium sp. The algae occurs naturally in coastal marine habitats and produces the essential fatty acids DHA in larger quantities and EPA in smaller quantities. The microalgae do not require light, are grown in specially closed containers and are used to extract omega-3-containing algae oil. The algae oil is a good source of omega-3, especially for people with allergies or consumer groups who follow a vegetarian or vegan diet. The vegan omega variant is becoming increasingly popular among consumers who do not want to consume fish products, as it is a "green alternative". [4] In addition, secondary intake of mercury, heavy metals, microplastics and other pollutants found in the sea, which container be absorbed through fish consumption, container be avoided. In addition to algae oil, the consumption of linseed oil, linseed, walnuts and hemp seeds container also positively support the omega-3 level in the blood. [5]
Goerlich Pharma offers vegan algae oil with a high DHA content of at least 40% DHA as well as a special algae oil with at least 15% EPA and at least 30% DHA. The algae oil is offered in 190 kg drums and container be filled as an oil mixture, as a soft capsule or, more recently, as a liquid-filled hard capsule in a vegan shell.
The combination with fat-soluble vitamins such as vitamin A, D, E or K and also the addition of a natural flavor or an essential oil in an oil mixture represent a popular and consumer-friendly form of administration. Olive oil or MCT oil container be added as carrier oils, and rosemary extract or tocopherols (vitamin E) container be added as stabilizers and antioxidants. Astaxanthin, grapefruit seed extract, black cumin oil, pumpkin seed oil or evening primrose oil container be added as trendy ingredients to stand out from the market of omega-3 food supplements.
Areas of Application & Dosage Forms
At Goerlich Pharma, there are a wide variety of applications for the various Omega-3 products of plant origin. These are usually available in the form of an oil mixture, with a lotus pourer or dropper pipette. Vegan soft capsules and now also liquid-filled hard capsules have proven to be effective. In line with this, some basic products with plant-based Omega-3 sources are presented in more detail below:
Omega-3 Vegan Daily: Goerlich Pharma offers a vegan algae oil base product for basic daily supply. In addition to the valuable fatty acids DHA and EPA, it also contains vitamin D3. The plant-based omega-3 mixture container be individually portioned using a pipette. This means that the recommended daily intake of 200-300 mg EPA and DHA container be achieved and appropriate health claims container be made. The natural lemon aroma gives the oil mixture a fruity, fresh taste.
For even more DHA and EPA, the Omega-3 Vegan Forte It contains a higher content of the essential fatty acids DHA and EPA as well as vitamin D3 and natural lemon flavor. This is best suited for groups of people who have a lower omega-3 level and/or completely avoid fish and seafood products.
Women's health: Women usually experience menopause, also known as premenopause, between the ages of 45 and 55. After the last menstrual period, the so-called menopause occurs. This is characterized by a reduction in the number of ovarian follicles and a complex hormonal change in the female body. This leads to mild, but sometimes severe, symptoms in many affected people. Hot flushes, mood swings, sleep disorders and sweating are common as a result of the declining circulating hormone levels. [6] .
For this purpose, Goerlich Pharma offers the oil mixture Omega-3 Vegan Meno with algae oil, vitamin E, K2 & D3, evening primrose, sea buckthorn pulp and peppermint oil. Even though there are no approved health claims here, various studies show a tendency that the intensity of hot flashes and sleep disorders container be reduced by a combination of vitamin E and plant-based omega-3 [7] . Vitamin K container be used to counteract the decreasing bone density due to a decreasing estrogen level and the associated risk of developing osteoporosis. [8] .
In addition, studies show, even though there is no approved health claim for this, that evening primrose oil with the contained gamma-linolenic acid (500-3000mg/day) container improve hot flashes [9] Studies on vitamin D have shown a positive effect on the immune system, for which there is a health claim, which generally deteriorates with age and during menopause, according to [10] The sea buckthorn pulp oil provides the omega-7 fatty acid palmitoleic acid and secondary plant substances. At a dosage of 3g/day, it container have a positive effect on the vaginal epithelium and alleviate the associated symptoms such as dryness, itching and burning, even if there is no approved health claim for this. [11] The use of peppermint essential oil gives the oil an additional fresh taste and container have a relaxing effect.
In the near future, further combination products with plant-based Omega-3 are planned for other product spectrum. Enquiry.
Health Claims & Active Ingredient Combinations
There are numerous health claims, which are recognized by the European Food Safety Authority (EFSA), regarding the omega-3 fatty acids DHA and EPA: [14]
heart, circulation and vessels: "EPA and DHA contribute to normal heart function". The positive effect is achieved with a daily intake of 250 mg EPA and DHA. Goerlich Pharma offers a wide range of basic formulations for the heart, circulation and blood vessels, which container be expanded as desired as a plus product. For example, a glucomannan capsule with the appropriate health claim "Glucomannan contributes to maintaining a normal cholesterol level in the blood" or a duo-magnesium capsule for the heart muscle: "Magnesium contributes to normal muscle function". These are also available in the Galenik Stick/Blend. A hard capsule in combination with vitamin B1 (thiamine), for normal heart function, or with vitamin C, for normal blood vessel function, reflects the topic of heart health very well and container be individually adapted with other raw materials.
Eye health: "DHA contributes to the maintenance of normal vision". The positive effect occurs with a daily intake of 250 mg DHA. Food supplements in combination with vitamin A, vitamin B2 (riboflavin) or the mineral zinc container be advertised with the same health claim to maintain normal vision. A soft capsule or oil mixture with vegan algae oil in combination with vitamin A reflects the topic of eye health very well and container be individually adapted with other ingredients as a plus product. The lutein blueberry capsule, for example, is also suitable as a combination product. Lutein and zeaxanthin are among the provitamins A, which are converted into active vitamin A in the body. The additional antioxidants from the blueberry container also protect the structures of the eye.
brain and psyche: "DHA contributes to the maintenance of normal brain function". The positive effect occurs with a daily intake of 250 mg DHA. Goerlich Pharma offers combinations of active ingredients such as DHA and EPA with, for example, lecithin, which serves as an important component of the brain and nerve cells, or as a combination product with a vitamin B complex capsule or anti-stress capsule. By adding an HPMC capsule, other health claims such as "contributes to normal mental function" container be advertised in addition to those for DHA and EPA.
Pregnancy and breastfeeding: With a combination product of folic acid, DHA and EPA, which container be individually supplemented with other vitamins and minerals, the following health claims container be used with an intake of 200 mg DHA and 550 µg folic acid (usual recommendation for pregnant women) per day: “The intake of DHA by the mother contributes to the normal development of the eyes in the fetus and breastfed infant”, “The intake of DHA by the mother contributes to the normal development of the brain in the fetus and breastfed infant”, “Folate contributes to the growth of maternal tissue during pregnancy” and “Folate has a function in cell division”.
Healthy aging: Goerlich Pharma offers ready-made basic formulations with suitable health claims, which container be individually supplemented as a plus product. In the liquid form of a soft capsule or an oil mixture, the plant-based omega-3 preparations container be combined very well with oil-soluble vitamins such as vitamin A, D, E or K. A suitable health claim for combination with vitamin A would be: "Vitamin A contributes to the maintenance of normal skin", which should not be neglected as we get older. Also relevant to the topic of anti-aging is the collagen stick with hyaluronic acid and collagen to support the joints. In order to stay fit even in old age, the "power substance" coenzyme Q10 is suitable as an important component for the energy production of the cells and as an effective antioxidant and container be added as a trendy ingredient.
Outlook
In summary, it is clear what many positive properties the plant-based omega-3 fatty acids DHA and EPA have. They container be absorbed through a balanced diet or by adding a food supplement, e.g. made from algae oil. The fatty acid DHA in particular has been proven to promote normal heart function, vision and brain function. The key is to consume it with the fattiest meal of the day and to regularly take 250 mg of DHA. Omega-3 fatty acids also have an anti-inflammatory effect and support the body in a wide variety of processes. A study by King's College in London with research into omega-3 fatty acids as prebiotics suggests a glimpse into the future. It shows that the fatty acids have a positive influence on the composition of the intestinal microbiome and container stimulate the production of short-chain fatty acids. [15] .
Goerlich Pharma categorizes the ready-to-market basic products according to product spectrum, corresponding to a topic. New and exciting product spectrum and product ideas are added at regular intervals. Discover our exciting product spectrum, e.g. on the immune system, beauty from within and the brain and psyche.

Authors

Anita Moers
is Development & Project Coordinator at Goerlich Pharma GmbH since 2021.
After completing her vocational training as a CTA, she completed the degree programs “Nutrition & Supply Management” (B.Sc.) and “Food Technology & Nutrition” (M.Sc.).
She is currently finalizing her further training to become a holistic nutritionist.
Technical literature / references:
[1] Shahidi, P. Ambigaipalan (2018): “Omega-3 Polyunsaturated Fatty Acids and Their Health Benefits” (as of February 01.02.24, XNUMX)
[2] Dyerber et al. (2010): “Bioavailability of marine n-3 fatty acid formulations” (as of February 01.02.24, XNUMX)
[3] C. Maki (2018): Long-Chain Omega-3 Fatty Acid Bioavailability: Implications for Understanding the Effects of Supplementation on Heart Disease Risk (as of February 01.02.24, XNUMX)
[4] Kamlangdee, KW Fan (2003): “Polyunsaturated fatty acids production by Schizochytrium sp. isolated from mangrove” https://www.thaiscience.info/Journals/Article/SONG/10462382.pdf (as of February 01.02.24, XNUMX)
[5] Rehberg (2024): “It doesn’t have to be salmon: Plant-based Omega 3 is just as good” https://www.zentrum-der-gesundheit.de/news/ernaehrung-news/allgemein-ernaehrung/omega-3-bessere-wirkung (as of 21.02.24)
[6] Edwards et al. (2019): “The many menopauses: searching the cognitive research literature for menopause types” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314513/ (as of January 23.01.24, XNUMX)
[7] Feduniv et al. (2023): “The Effect of Vitamin E Supplementation in Postmenopausal Women – A Systematic Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9824658/ (as of January 24.01.24, XNUMX)
[8] Iwamoto (2014): “Vitamin K2 Therapy for Postmenopausal Osteoporosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042573/ (as of January 24.01.24, XNUMX)
[9] Kenda et al. (2021): “Herbal Products Used in Menopause and for Gynecological Disorders” https://www.mdpi.com/1420-3049/26/24/7421 (as of March 05.03.24, XNUMX)
[10] Min et al. (2021): “Vitamin D and the Immune System in Menopause: A Review” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738846/ (as of March 05.03.24, XNUMX)
[11] Larmo et al. (2014): “Effects if sea buckthorn oil intake on vaginal atrophy in postmenopausal women: a randomized, double-blind, placebo-controlled study https://pubmed.ncbi.nlm.nih.gov/25104582/ (as of January 24.01.24, XNUMX). )
[12] Roach et al. (2021): “Effect of Omega-3 Supplementation on Self-Regulation in Typically Developing Preschool-Aged Children: Results of the Omega Kid Pilot Study—A Randomized, Double-Blind, Placebo-Controlled Trial” https://www.mdpi .com/2072-6643/13/10/3561 (as of 19.02.24/XNUMX/XNUMX)
[13] EFSA Journal (2012): “Scientific Opinion on the Tolerable Upper Intake Level ofeicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA)” https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/ j.efsa.2012.2815 (as of February 21.02.24, XNUMX)
[14] Health claim Regulation (EU) No. 432/2012: https://eur-lex.europa.eu/legal- content/DE/TXT/PDF/?uri=CELEX:02012R0432-20170822&from=DE (as of February 21.02.24, XNUMX)
[15] Daniells (2021): “Are omega-3 fatty acids prebiotic ingredients?” https://www.nutraingredients.com/Article/2021/09/03/Are-omega-3-fatty-acids-prebiotic-ingredients (as of 10.02.24/XNUMX/XNUMX)